-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001104659-11-018940.txt : 20110406
<SEC-HEADER>0001104659-11-018940.hdr.sgml : 20110406
<ACCEPTANCE-DATETIME>20110406171027
ACCESSION NUMBER:		0001104659-11-018940
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20110406
FILED AS OF DATE:		20110406
DATE AS OF CHANGE:		20110406

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			HIG GP II INC
		CENTRAL INDEX KEY:			0001173671

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-35119
		FILM NUMBER:		11743837

	BUSINESS ADDRESS:	
		STREET 1:		1001 BRICKELL BAY DR
		STREET 2:		27TH FL
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33131

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			TAMER ANTHONY
		CENTRAL INDEX KEY:			0001050045

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-35119
		FILM NUMBER:		11743835

	MAIL ADDRESS:	
		STREET 1:		1001 SOUTH BAYSHORE DRIVE
		STREET 2:		STE 2708
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33131

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			MNAYMNEH SAMI
		CENTRAL INDEX KEY:			0001050046

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-35119
		FILM NUMBER:		11743836

	MAIL ADDRESS:	
		STREET 1:		1001 SOUTH BAYSHORE DRIVE
		STREET 2:		STE 2708
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33131

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Davidson Aaron
		CENTRAL INDEX KEY:			0001515825

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-35119
		FILM NUMBER:		11743834

	MAIL ADDRESS:	
		STREET 1:		4819 EMPEROR BOULEVARD
		STREET 2:		SUITE 400
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			TRANZYME INC
		CENTRAL INDEX KEY:			0001274644
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				631192270
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		4819 EMPEROR BOULEVARD, SUITE 400
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703
		BUSINESS PHONE:		919 313-4760

	MAIL ADDRESS:	
		STREET 1:		4819 EMPEROR BOULEVARD, SUITE 400
		CITY:			DURHAM
		STATE:			NC
		ZIP:			27703

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			H.I.G. Ventures - Tranzyme, LLC
		CENTRAL INDEX KEY:			0001515804
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-35119
		FILM NUMBER:		11743838

	BUSINESS ADDRESS:	
		STREET 1:		1450 BRICKELL AVENUE
		STREET 2:		31ST FLOOR
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33131
		BUSINESS PHONE:		919-313-4760

	MAIL ADDRESS:	
		STREET 1:		1450 BRICKELL AVENUE
		STREET 2:		31ST FLOOR
		CITY:			MIAMI
		STATE:			FL
		ZIP:			33131
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>a4.xml
<DESCRIPTION>4
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2011-04-06</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001274644</issuerCik>
        <issuerName>TRANZYME INC</issuerName>
        <issuerTradingSymbol>TZYM</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001515804</rptOwnerCik>
            <rptOwnerName>H.I.G. Ventures - Tranzyme, LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O H.I.G. CAPITAL</rptOwnerStreet1>
            <rptOwnerStreet2>1450 BRICKELL AVENUE, 31ST FLOOR</rptOwnerStreet2>
            <rptOwnerCity>MIAMI</rptOwnerCity>
            <rptOwnerState>FL</rptOwnerState>
            <rptOwnerZipCode>33131</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001173671</rptOwnerCik>
            <rptOwnerName>HIG GP II INC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O H.I.G. CAPITAL</rptOwnerStreet1>
            <rptOwnerStreet2>1450 BRICKELL AVENUE, 31ST FLOOR</rptOwnerStreet2>
            <rptOwnerCity>MIAMI</rptOwnerCity>
            <rptOwnerState>FL</rptOwnerState>
            <rptOwnerZipCode>33131</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001050046</rptOwnerCik>
            <rptOwnerName>MNAYMNEH SAMI</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O H.I.G. CAPITAL</rptOwnerStreet1>
            <rptOwnerStreet2>1450 BRICKELL AVENUE, 31ST FLOOR</rptOwnerStreet2>
            <rptOwnerCity>MIAMI</rptOwnerCity>
            <rptOwnerState>FL</rptOwnerState>
            <rptOwnerZipCode>33131</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001050045</rptOwnerCik>
            <rptOwnerName>TAMER ANTHONY</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O H.I.G. CAPITAL</rptOwnerStreet1>
            <rptOwnerStreet2>1450 BRICKELL AVENUE, 31ST FLOOR</rptOwnerStreet2>
            <rptOwnerCity>MIAMI</rptOwnerCity>
            <rptOwnerState>FL</rptOwnerState>
            <rptOwnerZipCode>33131</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001515825</rptOwnerCik>
            <rptOwnerName>Davidson Aaron</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O H.I.G. CAPITAL</rptOwnerStreet1>
            <rptOwnerStreet2>1450 BRICKELL AVENUE, 31ST FLOOR</rptOwnerStreet2>
            <rptOwnerCity>MIAMI</rptOwnerCity>
            <rptOwnerState>FL</rptOwnerState>
            <rptOwnerZipCode>33131</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2011-04-06</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>C</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>2189791</value>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>2189791</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                    <footnoteId id="F2"/>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2011-04-06</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>812500</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>4.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3002291</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                    <footnoteId id="F2"/>
                    <footnoteId id="F3"/>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Series A Convertible Preferred Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F1"/>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2011-04-06</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>C</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>15328551</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F1"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>2189791</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">Each share of the Issuer's Series A Convertible Preferred Stock automatically converted, for no additional consideration, into shares of Common Stock prior to the closing of the Issuer's initial public offering on a 7-for-1 basis, reflecting a 1-for-7 reverse stock split which became effective on March 31, 2011.</footnote>
        <footnote id="F2">These securities are owned of record by H.I.G. Ventures - Tranzyme, LLC (&quot;HIG LLC&quot;). H.I.G. - GPII, Inc. (&quot;GP II&quot;) is the manager of HIG LLC and has shared voting and dispositive power of the securities held by HIG LLC, but GP II disclaims beneficial ownership of such securities except to the extent of its pecuniary interest therein. The co-presidents, directors, and sole shareholders of GP II having shared voting and dispositive power over these securities are Sami Mnaymneh and Anthony Tamer, each of whom disclaims beneficial ownership of such securities except to the extent of his pecuniary interests therein.</footnote>
        <footnote id="F3">These shares were purchased in the Issuer's initial public offering.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Richard H. Siegel, Vice President and General Counsel</signatureName>
        <signatureDate>2011-04-06</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Richard H. Siegel, Vice President and General Counsel</signatureName>
        <signatureDate>2011-04-06</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Anthony Tamer</signatureName>
        <signatureDate>2011-04-06</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Sami W. Mnaymneh</signatureName>
        <signatureDate>2011-04-06</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Richard I. Eisenstadt for Aaron Davidson, Attorney-in-fact</signatureName>
        <signatureDate>2011-04-06</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----