X0303 4 2011-05-17 0 0001016169 ANTARES PHARMA, INC. AIS 0001049713 JACOB LEONARD S C/O ANTARES PHARMA, INC. 250 PHILLIPS BLVD, SUITE 290 EWING NJ 08618 1 0 0 0 Stock Option (right to buy) 1.66 2011-05-17 4 A 0 80000 A 2021-05-16 Common Stock 80000 596247 D Represents the annual grant, received by all Directors, under the Directors' Compensation Plan of options to purchase 40,000 shares of common stock, par value $0.01 per share, issued under the Antares Pharma, Inc. 2008 Equity Compensation Plan, and an additional grant under the Directors' Compensation Plan of options to purchase 40,000 shares of common stock for being Chairman of the Board. The option vests in four equal quarterly installments. Not applicable Robert F. Apple as attorney-in-fact for Leonard S. Jacob 2011-05-19