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Equity Incentive Plans and Warrants (Details 3) (USD $)
Share data in Thousands, except Per Share data, unless otherwise specified
12 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Company's stock option plans      
Shares Outstanding, Beginning Balance 1,819 1,209 787
Shares, Granted 551 884 784
Shares, Exercised (174) (2) (11)
Shares, Cancelled (203) (272) (351)
Shares Outstanding, Ending Balance 1,993 1,819 1,209
Shares Exercisable 715 600  
Weighted average exercise price per share, Beginning Balance $ 3.07 $ 5.56 $ 15.75
Weighted Average Exercise Price per share, Granted $ 4.08 $ 2.20 $ 2.90
Weighted average exercise Price per Share, exercised $ 2.86 $ 0.72 $ 1.37
Weighted average exercise price per share, Cancelled $ 3.12 $ 11.30 $ 22.62
Weighted average exercise price per share, Ending Balance $ 3.36 $ 3.07 $ 5.56
Weighted average remaining contractual term, Outstanding, Ending Balance 8 years 4 months 24 days    
Aggregate intrinsic value, Outstanding, Ending Balance $ 257,000    
Weighted Average Exercise Price per Share $ 3.76    
Weighted Average Remaining Contractual Term 7 years 8 months 12 days    
Aggregate intrinsic value of options exercisable $ 81,000 $ 8,000