Balance Sheet Details (Details 1) (USD $) In Thousands, unless otherwise specified	12 Months Ended
	Dec. 31, 2012	Sep. 30, 2012	Jun. 30, 2012	Mar. 31, 2012	Dec. 31, 2011	Sep. 30, 2011	Jun. 30, 2011
Property and equipment
Property and equipment, gross	$ 63,246				$ 39,868
Less: Accumulated depreciation and amortization	(26,448)				(24,257)
Property and equipment, net	36,798	36,861	34,446	22,802	15,611	11,208	6,712
Property and equipment estimated useful life	10 years
Maximum [Member]
Property and equipment
Leasehold improvements	5 years
Minimum [Member]
Property and equipment
Leasehold improvements	3 Years
Laboratory, machinery and equipment [Member]
Property and equipment
Property and equipment, gross	28,308				24,927
Laboratory, machinery and equipment [Member] | Maximum [Member]
Property and equipment
Property and equipment estimated useful life	5 years
Laboratory, machinery and equipment [Member] | Minimum [Member]
Property and equipment
Property and equipment estimated useful life	3 years
Computer equipment [Member]
Property and equipment
Property and equipment, gross	4,350				3,031
Property and equipment estimated useful life	3 years
Furniture and fixtures [Member]
Property and equipment
Furniture and fixtures	899				0
Property and equipment estimated useful life	5 years
Building [Member]
Property and equipment
Property and equipment, gross	18,748				7,298
Property and equipment estimated useful life	40 years
Leasehold improvements [Member]
Property and equipment
Property and equipment, gross	4,529				506
Leasehold improvements	Over term of lease
Construction in progress [Member]
Property and equipment
Property and equipment, gross	$ 6,412				$ 4,106