Debt (Tables)

12 Months Ended

Dec. 31, 2012

Debt [Abstract]

Future maturities and interest payments of the Company's long term debt

	December 31, 2012
	Term Loan			Equipment Loan			Total
Fiscal year 2013	$	2,588		$	437		$	3,025
Fiscal year 2014		2,588			437			3,025
Fiscal year 2015		2,588			437			3,025
Fiscal year 2016		2,588			437			3,025
Fiscal year 2017		24,922			437			25,359
Thereafter		0			2,149			2,149
Total minimum payments		35,274			4,334			39,608
Less amount representing interest		(12,774	)		(1,444	)		(14,218	)
Gross balance of long term debt		22,500			2,890			25,390
Plus derivative liability (1)		3,875			0			3,875
Less unamortized debt discount (2)		(4,187	)		0			(4,187	)
Total carrying value		22,188			2,890			25,078
Less current portion		0			(217	)		(217	)
Total carrying value, noncurrent portion	$	22,188		$	2,673		$	24,861

(1) Represents the detachable warrants issued to Athyrium, as further described below. The Company had the intent and the ability as of December 31, 2012 to settle the warrants in shares of common stock. As such, the asserted derivative liability was included in long term debt carrying value on its consolidated financial statements at December 31, 2012.

(2) Includes the initial fair value of the detachable warrants in addition to cash fees paid to Athyrium.

Difference between the carrying value of notes repurchased and principal repurchase price

	For the Years Ended December 31,
	2011			2010
Principal	$	39,889		$	21,000
Debt premium (discount), net		9,253			(3,944	)
Compound embedded derivative		5,072			311
Issuance costs		(220	)		(201	)
Carrying value		53,994			17,166
Principal repurchase price		38,645			20,550
Gain (loss) on debt extinguishment	$	15,349		$	(3,384	)