Balance Sheet Details (Details 1) (USD $) In Thousands, unless otherwise specified	Sep. 30, 2012	Dec. 31, 2011
Property and equipment
Property and equipment, gross	$ 39,720	$ 32,064
Less: Accumulated depreciation and amortization	(25,374)	(24,258)
Property and equipment, net	14,346	7,806
Laboratory, machinery and equipment [Member]
Property and equipment
Property and equipment, gross	28,171	24,927
Computer equipment [Member]
Property and equipment
Property and equipment, gross	4,305	3,031
Furniture and fixtures [Member]
Property and equipment
Furniture and fixtures	880	0
Construction in progress [Member]
Property and equipment
Property and equipment, gross	$ 6,364	$ 4,106

The cumulative amount of depreciation, depletion and amortization (related to property, plant and equipment, but not including land) that has been recognized in the income statement.

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Gross amount of long-lived physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment.

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- Definition

Amount, net of accumulated depreciation, depletion and amortization, of long-lived physical assets used in the normal conduct of business and not intended for resale. Examples include, but are not limited to, land, buildings, machinery and equipment, office equipment, furniture and fixtures, and computer equipment.

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