1933 Act File No. 333-40455
1940 Act File No. 811-08495
AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON JANUARY 12, 2010
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM N-1A
REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933			[X]
Post-Effective Amendment No. 99			[X]
and/or
REGISTRATION STATEMENT UNDER THE INVESTMENT COMPANY ACT OF 1940
Amendment No. 100			[X]
(Check appropriate box or boxes)
NATIONWIDE MUTUAL FUNDS
(EXACT NAME OF REGISTRANT AS SPECIFIED IN CHARTER)
1000 CONTINENTAL DRIVE, SUITE 400
KING OF PRUSSIA, PENNSYLVANIA 19406
(ADDRESS OF PRINCIPAL EXECUTIVE OFFICE) (ZIP CODE)
Registrant's Telephone Number, including Area Code: (610) 230-1300
Send Copies of Communications to:
ALLAN J. OSTER, ESQ.		BARBARA A. NUGENT, ESQ.
1000 CONTINENTAL DRIVE, SUITE 400		STRADLEY RONON STEVENS & YOUNG, LLP
KING OF PRUSSIA, PENNSYLVANIA 19406		2600 ONE COMMERCE SQUARE
(NAME AND ADDRESS OF AGENT FOR SERVICE)		PHILADELPHIA, PENNSYLVANIA 19103
It is proposed that this filing will become effective: (check appropriate box)
[  ]	immediately upon filing pursuant to paragraph (b)
[X]	on March 1, 2010 pursuant to paragraph (b)
[  ]	60 days after filing pursuant to paragraph (a)(1)
[  ]	on [date] pursuant to paragraph (a)(1)
[  ]	75 days after filing pursuant to paragraph (a)(2)
[  ]	on [date] pursuant to paragraph (a)(2) of rule 485.
If appropriate, check the following box:
[X]	This post-effective amendment designated a new effective date for a previously filed post-effective amendment.

Explanatory Note

This Post-Effective Amendment No. 99, Amendment No. 100 to Registrant's Registration Statement on Form N-1A (the "Amendment") is being filed under Rule 485(b)(1)(iii) and incorporates by reference (i) the Prospectus for the Nationwide Bond Fund, Nationwide Enhanced Income Fund, Nationwide Government Bond Fund, Nationwide Money Market Fund, Nationwide Short Duration Bond Fund, Nationwide Bond Index Fund, Nationwide International Index Fund, Nationwide Mid Cap Market Index Fund, Nationwide S&P 500 Index Fund, Nationwide Small Cap Index Fund, Nationwide Investor Destinations Aggressive Fund, Nationwide Investor Destinations Moderately Aggressive Fund, Nationwide Investor Destinations Moderate Fund, Nationwide Investor Destinations Moderately Conservative Fund, Nationwide Investor Destinations Conservative Fund, Nationwide Fund, Nationwide Growth Fund, Nationwide Large Cap Value Fund, Nationwide Value Fund, Nationwide International Value Fund, Nationwide U.S. Small Cap Value Fund, Nationwide Destination 2010 Fund, Nationwide Destination 2015 Fund, Nationwide Destination 2020 Fund, Nationwide Destination 2025 Fund, Nationwide Destination 2030 Fund, Nationwide Destination 2035 Fund, Nationwide Destination 2040 Fund, Nationwide Destination 2045 Fund, Nationwide Destination 2050 Fund and Nationwide Retirement Income Fund; (ii) the Statements of Additional Information for the aforementioned funds; and (iii) the Part C.  This Amendment is being filed for the purposes of delaying the effectiveness of Post-Effective Amendment No. 98, Amendment No. 99 until March 1, 2010.

SIGNATURES

Pursuant to the requirements of the Securities Act of 1933, as amended, and the Investment Company Act of 1940, as amended, the Registrant certifies that it meets all of the requirements for the effectiveness of this Registration Statement pursuant to Rule 485(b) under the Securities Act of 1933 and has duly caused this Post-Effective Amendment No. 99, Amendment No. 100 to this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of King of Prussia, and Commonwealth of Pennsylvania, on this 12th day of January, 2010.

NATIONWIDE MUTUAL FUNDS

By: /s/Allan J. Oster                                              

Allan J. Oster, Attorney-In-Fact for Registrant

PURSUANT TO THE REQUIREMENT OF THE SECURITIES ACT OF 1933, THIS POST-EFFECTIVE AMENDMENT NO. 99, AMENDMENT NO. 100 TO THE REGISTRATION STATEMENT HAS BEEN SIGNED BELOW BY THE FOLLOWING PERSONS IN THE CAPACITIES INDICATED ON THE 12TH DAY OF JANUARY, 2010.

Signature & Title

Principal Executive Officer

/s/ Michael S. Spangler*                                                                

Michael S. Spangler, President and

Chief Executive Officer

Principal Accounting and Financial Officer

/s/ Joseph Finelli*                                                      

Joseph Finelli, Treasurer and Chief Financial Officer

/s/ Charles E. Allen*                                                                

Charles E. Allen, Trustee

/s/ Paula H.J. Cholmondeley*                                                                

Paula H.J. Cholmondeley, Trustee

/s/ C. Brent Devore*                                                                

C. Brent Devore, Trustee

/s/ Phyllis Kay Dryden*                                                                

Phyllis Kay Dryden, Trustee

/s/ Barbara L. Hennigar*                                                                

Barbara L. Hennigar, Trustee

/s/ Barbara I. Jacobs*                                                                

Barbara I. Jacobs, Trustee

/s/ Douglas F. Kridler*                                                                

Douglas F. Kridler, Trustee

/s/ David C. Wetmore*                                                      

David C. Wetmore, Trustee and Chairman

*BY:  /s/Allan J. Oster                                                                                        

          Allan J. Oster, Attorney-In Fact