X0306 4 2019-03-21 0 0001048477 BIOMARIN PHARMACEUTICAL INC BMRN 0001557533 Ajer Jeffrey Robert C/O BIOMARIN PHARMACEUTICAL INC., 105 DIGITAL DRIVE NOVATO CA 94949 0 1 0 0 EVP, Chief Commercial Officer Common Stock 2019-03-21 4 S 0 2589 89.6175 D 56659 D Common Stock 2019-03-21 4 S 0 1930 90.4737 D 54729 D Trade made pursuant to a 10b5-1 plan executed on September 10, 2018. The price in column 4 is the weighted average price. The price actually received ranged from $89.09 to $90.08. The reporting person shall provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price. The price in column 4 is the weighted average price. The price actually received ranged from $90.11 to $90.80. The reporting person shall provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price. /s/ Eric Fleekop, Attorney-in-Fact 2019-03-25