Schedule of Property Plant and Equipment Net (Detail) - USD ($) $ in Thousands	Jun. 30, 2018	Dec. 31, 2017
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	$ 1,341,136	$ 1,303,434
Accumulated depreciation	(440,656)	(406,734)
Total property, plant and equipment, net	900,480	896,700	[1]
Building and Improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	674,682	663,347
Manufacturing and Laboratory Equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	316,331	294,521
Computer Hardware and Software
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	152,010	144,268
Leasehold Improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	38,352	42,572
Furniture and Equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	30,833	31,515
Land Improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	5,977	5,331
Land
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	62,369	62,369
Construction-in-Progress
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	$ 60,582	$ 59,511

[1] December 31, 2017 balances were derived from the audited Consolidated Financial Statements included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2017, filed with the SEC on February 26, 2018.