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PROPERTY, PLANT AND EQUIPMENT (Tables)
6 Months Ended
Jun. 30, 2018
Property Plant And Equipment [Abstract]  
Schedule of Property Plant and Equipment Net

Property, plant and equipment, net consisted of the following:

 

 

 

June 30,

 

 

December 31,

 

 

 

2018

 

 

2017

 

Building and improvements

 

$

674,682

 

 

$

663,347

 

Manufacturing and laboratory equipment

 

 

316,331

 

 

 

294,521

 

Computer hardware and software

 

 

152,010

 

 

 

144,268

 

Leasehold improvements

 

 

38,352

 

 

 

42,572

 

Furniture and equipment

 

 

30,833

 

 

 

31,515

 

Land improvements

 

 

5,977

 

 

 

5,331

 

Land

 

 

62,369

 

 

 

62,369

 

Construction-in-progress

 

 

60,582

 

 

 

59,511

 

 

 

 

1,341,136

 

 

 

1,303,434

 

Accumulated depreciation

 

 

(440,656

)

 

 

(406,734

)

Total property, plant and equipment, net

 

$

900,480

 

 

$

896,700