PROPERTY, PLANT AND EQUIPMENT (Tables)

12 Months Ended

Dec. 31, 2017

Property Plant And Equipment [Abstract]

Schedule of Property Plant and Equipment Net

Property, plant and equipment, net, consisted of the following:

	December 31,
	2017			2016
Building and improvements	$	663,347		$	510,805
Manufacturing and laboratory equipment		294,521			242,899
Computer hardware and software		144,268			129,506
Leasehold improvements		42,572			44,184
Furniture and equipment		31,515			27,229
Land improvements		5,331			4,881
Land		62,369			55,412
Construction-in-progress		59,511			126,446
		1,303,434			1,141,362
Less: Accumulated depreciation	$	(406,734	)		(342,594	)
Total property, plant and equipment, net	$	896,700		$	798,768