CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2017	Jun. 30, 2016	Jun. 30, 2017	Jun. 30, 2016
REVENUES:
Net product revenues	$ 315,926	$ 298,576	$ 618,116	$ 533,933
Royalty and other revenues	1,522	1,555	3,077	2,934
Total revenues	317,448	300,131	621,193	536,867
OPERATING EXPENSES:
Cost of sales	56,305	51,617	106,311	94,735
Research and development	143,039	167,039	288,042	325,832
Selling, general and administrative	143,505	109,577	263,524	214,877
Intangible asset amortization and contingent consideration	13,411	(54,414)	22,336	(43,972)
Impairment of intangible assets	0	599,118	0	599,118
Total operating expenses	356,260	872,937	680,213	1,190,590
LOSS FROM OPERATIONS	(38,812)	(572,806)	(59,020)	(653,723)
Equity in the loss of BioMarin/Genzyme LLC	(220)	(135)	(743)	(270)
Interest income	2,983	1,357	6,055	2,928
Interest expense	(10,040)	(9,944)	(20,159)	(19,787)
Other income (expense)	543	(1,417)	4,015	(1,219)
LOSS BEFORE INCOME TAXES	(45,546)	(582,945)	(69,852)	(672,071)
Benefit from income taxes	(8,713)	(163,931)	(16,729)	(170,006)
NET LOSS	$ (36,833)	$ (419,014)	$ (53,123)	$ (502,065)
NET LOSS PER SHARE, BASIC AND DILUTED	$ (0.21)	$ (2.58)	$ (0.31)	$ (3.10)
Weighted average common shares outstanding, basic and diluted	174,374	162,587	173,547	162,067
COMPREHENSIVE LOSS	$ (56,511)	$ (414,533)	$ (80,597)	$ (518,570)