Business acquisition contingent consideration potential cash payments.

No definition available.

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- Definition

Finite lived intangible asset estimated useful life.

+ References

No definition available.

+ Details

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- Definition

License agreement amendment month and year.

+ References

No definition available.

+ Details

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- Definition

Amount of direct costs of the business combination including legal, accounting, and other costs incurred to consummate the business acquisition.

+ References

No definition available.

+ Details

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

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- Definition

The amortization method of a major finite-lived intangible asset class. A major class is composed of intangible assets that can be grouped together because they are similar either by their nature or by their use in the operations of a company. The straight-line method is the preferred amortization method, unless another method better reflects the pattern in which the asset is consumed.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 350
-SubTopic 30
-Section 35
-Paragraph 6
-URI http://asc.fasb.org/extlink&oid=66005732&loc=d3e15372-109273

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- Definition

The cash outflow associated with the acquisition of business during the period. The cash portion only of the acquisition price.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Glossary Investing Activities
-URI http://asc.fasb.org/extlink&oid=6516133

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
-SubTopic 10
-Section 45
-Paragraph 13
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=66902209&loc=d3e3213-108585

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- Details

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- Details

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Acquisitions - Additional Information (Detail) - Merck Serono $ in Thousands, € in Millions			3 Months Ended	12 Months Ended
	Mar. 31, 2017	Jan. 02, 2016 USD ($)	Mar. 31, 2017	Dec. 31, 2016 USD ($)	Dec. 31, 2016 EUR (€)	Jan. 01, 2016 USD ($)	Dec. 31, 2015 USD ($)
Business Acquisition [Line Items]
Business combination transaction costs \| $				$ 300		$ 600	$ 300
Business acquisition, cash paid \| $		$ 374,545		$ 374,500
Estimated useful life			through 2024
Intangible assets amortization method			straight-line basis
A&R Kuvan Agreement
Business Acquisition [Line Items]
Maximum potential additional consideration milestone payments \| €					€ 60.0
Pegvaliase Agreement
Business Acquisition [Line Items]
Maximum potential additional consideration milestone payments \| €					€ 125.0
License agreement amendment date	2016-12