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PROPERTY, PLANT AND EQUIPMENT (Tables)
12 Months Ended
Dec. 31, 2016
Property Plant And Equipment [Abstract]  
Schedule of Property Plant and Equipment Net

Property, plant and equipment, net consisted of the following:

 

 

 

December 31,

 

 

 

2016

 

 

2015

 

Building and improvements

 

$

510,805

 

 

$

442,100

 

Manufacturing and laboratory equipment

 

 

242,899

 

 

 

145,313

 

Computer hardware and software

 

 

129,506

 

 

 

113,442

 

Leasehold improvements

 

 

44,184

 

 

 

44,247

 

Furniture and equipment

 

 

27,229

 

 

 

22,817

 

Land improvements

 

 

4,881

 

 

 

4,881

 

Land

 

 

55,412

 

 

 

45,727

 

Construction-in-progress

 

 

126,446

 

 

 

164,283

 

 

 

 

1,141,362

 

 

 

982,810

 

Less: Accumulated depreciation

 

 

(342,594

)

 

 

(278,603

)

Total property, plant and equipment, net

 

$

798,768

 

 

$

704,207