Amounts Reclassified out of Accumulated Other Comprehensive Income (Detail) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Reclassification Adjustment Out Of Accumulated Other Comprehensive Income [Line Items]
Net product revenues	$ 1,110,381	$ 884,522	$ 738,416
Selling, general and administrative	476,593	402,271	302,156
LOSS FROM OPERATIONS	(803,429)	(110,702)	(92,891)
Other income (expense)	4,929	(9,462)	(395)
LOSS BEFORE INCOME TAXES	(831,050)	(154,724)	(124,868)
Provision for (benefit from) income taxes	(200,840)	17,075	9,101
NET LOSS	(630,210)	(171,799)	$ (133,969)
Amount Reclassified from AOCI (Gain) Loss
Reclassification Adjustment Out Of Accumulated Other Comprehensive Income [Line Items]
LOSS BEFORE INCOME TAXES	(115)	1,873
Provision for (benefit from) income taxes	42	681
NET LOSS	10,116	20,796
Amount Reclassified from AOCI (Gain) Loss | Other-than-temporary impairment on available-for-sale securities
Reclassification Adjustment Out Of Accumulated Other Comprehensive Income [Line Items]
Other income (expense)	0	(1,160)
Amount Reclassified from AOCI (Gain) Loss | Gain on Cash Flow Hedges
Reclassification Adjustment Out Of Accumulated Other Comprehensive Income [Line Items]
LOSS FROM OPERATIONS	10,273	19,604
Amount Reclassified from AOCI (Gain) Loss | Gain on Cash Flow Hedges | Forward Foreign Currency Exchange Contracts
Reclassification Adjustment Out Of Accumulated Other Comprehensive Income [Line Items]
Net product revenues	6,112	17,715
Selling, general and administrative	4,161	1,889
Amount Reclassified from AOCI (Gain) Loss | Gain (Loss) on Sale of Available-for-Sale Securities
Reclassification Adjustment Out Of Accumulated Other Comprehensive Income [Line Items]
Other income (expense)	$ (115)	$ 3,033