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PROPERTY, PLANT AND EQUIPMENT (Tables)
12 Months Ended
Dec. 31, 2015
Property Plant And Equipment [Abstract]  
Schedule of Property Plant and Equipment Net

Property, plant and equipment, net consisted of the following:

 

 

 

December 31,

 

 

 

2015

 

 

2014

 

Building and improvements

 

$

442,100

 

 

$

335,991

 

Manufacturing and laboratory equipment

 

 

145,313

 

 

 

124,564

 

Computer hardware and software

 

 

113,442

 

 

 

97,032

 

Leasehold improvements

 

 

44,247

 

 

 

39,297

 

Furniture and equipment

 

 

22,817

 

 

 

13,717

 

Land improvements

 

 

4,881

 

 

 

4,106

 

Land

 

 

45,727

 

 

 

29,358

 

Construction-in-progress

 

 

164,283

 

 

 

108,340

 

 

 

 

982,810

 

 

 

752,405

 

Less: Accumulated depreciation

 

 

(278,603

)

 

 

(228,889

)

Total property, plant and equipment, net

 

$

704,207

 

 

$

523,516