CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Dec. 31, 2015	Dec. 31, 2014
Current assets:
Cash and cash equivalents	$ 397,040	$ 875,486
Short-term investments	195,579	69,706
Accounts receivable, net (allowance for doubtful accounts: $93 and $490, at December 31, 2015 and 2014, respectively)	164,959	144,472
Inventory	271,683	199,452
Other current assets	60,378	108,524
Total current assets	1,089,639	1,397,640
Noncurrent assets:
Long-term investments	425,652	97,856
Property, plant and equipment, net	704,207	523,516
Intangible assets, net	683,996	156,578
Goodwill	197,039	54,258
Deferred tax assets	220,191	190,974
Other assets	408,644	54,557
Total assets	3,729,368	2,475,379
Current liabilities:
Accounts payable and accrued liabilities	392,511	231,844
Short-term contingent acquisition consideration payable	52,946	3,895
Total current liabilities	445,457	235,739
Noncurrent liabilities:
Long-term convertible debt, net	662,286	642,902
Long-term contingent acquisition consideration payable	32,663	38,767
Long-term deferred tax liabilities	143,527
Other long-term liabilities	44,588	30,077
Total liabilities	1,328,521	947,485
Stockholders’ equity:
Common stock, $0.001 par value: 250,000,000 shares authorized at December 31, 2015 and 2014: 161,526,044 and 149,093,647 shares issued and outstanding at December 31, 2015 and 2014, respectively.	162	149
Additional paid-in capital	3,414,837	2,359,744
Company common stock held by Nonqualified Deferred Compensation Plan	(13,616)	(9,695)
Accumulated other comprehensive income	21,033	27,466
Accumulated deficit	(1,021,569)	(849,770)
Total stockholders’ equity	2,400,847	1,527,894
Total liabilities and stockholders’ equity	$ 3,729,368	$ 2,475,379