Condensed Consolidated Statements Of Operations (USD $) In Thousands, except Per Share data	3 Months Ended		9 Months Ended
	Sep. 30, 2011	Sep. 30, 2010	Sep. 30, 2011	Sep. 30, 2010
REVENUES:
Net product revenues	$ 112,891	$ 96,559	$ 331,583	$ 271,224
Collaborative agreement revenues	97	130	375	507
Royalty and license revenues	437	1,061	1,554	2,922
Total revenues	113,425	97,750	333,512	274,653
OPERATING EXPENSES:
Cost of sales (excludes amortization of developed product technology)	22,445	18,003	62,504	49,816
Research and development	58,577	39,366	156,466	105,112
Selling, general and administrative	44,880	38,348	126,969	109,625
Intangible asset amortization and contingent consideration	3,040	3,972	28	6,206
Total operating expenses	128,942	99,689	345,967	270,759
INCOME (LOSS) FROM OPERATIONS	(15,517)	(1,939)	(12,455)	3,894
Equity in the loss of BioMarin/Genzyme LLC	(608)	(639)	(1,817)
Interest income	722	968	2,302	3,193
Interest expense	(2,432)	(3,008)	(6,645)	(8,072)
Debt conversion expense	(1,896)	0	(1,896)	0
Net gain from sale of investments	0	0	0	927
INCOME (LOSS) BEFORE INCOME TAXES	(19,731)	(4,618)	(20,511)	(2,252)
Provision for (benefit from) income taxes	(2,078)	(221,952)	6,590	(220,260)
NET INCOME (LOSS)	$ (17,653)	$ 217,334	$ (27,101)	$ 218,008
NET INCOME (LOSS) PER SHARE, BASIC	$ (0.16)	$ 2.13	$ (0.24)	$ 2.14
NET INCOME (LOSS) PER SHARE, DILUTED	$ (0.16)	$ 1.68	$ (0.24)	$ 1.74
Weighted average common shares outstanding, basic	112,290	102,110	111,358	101,660
Weighted average common shares outstanding, diluted	112,290	131,278	111,358	130,821