Condensed Consolidated Balance Sheets (USD $) In Thousands	Sep. 30, 2011	Dec. 31, 2010
Current assets:
Cash and cash equivalents	$ 71,254	$ 88,079	[1]
Short-term investments	153,120	186,033	[1]
Accounts receivable, net (allowance for doubtful accounts: $839 and $63, respectively)	107,057	86,576	[1]
Inventory	115,628	109,698	[1]
Other current assets	39,965	33,874	[1]
Total current assets	487,024	504,260	[1]
Investment in BioMarin/Genzyme LLC	1,168	1,082	[1]
Long-term investments	145,640	128,171	[1]
Property, plant and equipment, net	266,190	221,866	[1]
Intangible assets, net	100,780	103,648	[1]
Goodwill	51,543	53,364	[1]
Long-term deferred tax assets	229,172	236,017	[1]
Other assets	13,559	14,215	[1]
Total assets	1,295,076	1,262,623	[1]
Current liabilities:
Accounts payable and accrued liabilities	83,254	83,844	[1]
Total current liabilities	83,254	83,844	[1]
Convertible debt	348,339	377,521	[1]
Other long-term liabilities	88,944	84,001	[1]
Total liabilities	520,537	545,366	[1]
Stockholders' equity:
Common stock, $0.001 par value: 250,000,000 shares authorized at September 30, 2011 and December 31, 2010: 114,149,780 and 110,634,465 shares issued and outstanding at September 30, 2011 and December 31, 2010, respectively	114	111	[1]
Additional paid-in capital	1,175,422	1,090,188	[1]
Company common stock held by Nonqualified Deferred Compensation Plan	(3,935)	(1,965)	[1]
Accumulated other comprehensive income	1,304	188	[1]
Accumulated deficit	(398,366)	(371,265)	[1]
Total stockholders' equity	774,539	717,257	[1]
Total liabilities and stockholders' equity	$ 1,295,076	$ 1,262,623	[1]

[1] December 31, 2010 balances were derived from the audited consolidated financial statements.