X0306 4 2016-05-23 0 0001048477 BIOMARIN PHARMACEUTICAL INC BMRN 0001238403 SPIEGELMAN DANIEL K C/O BIOMARIN PHARMACEUTICAL INC., 770 LINDARO ST. SAN RAFAEL CA 94901 0 1 0 0 EVP, Chief Financial Officer Common Stock 2016-05-23 2016-05-23 4 S 0 3769 87.0746 D 58644 D Trade made pursuant to a 10b5-1 plan executed on May 9, 2016. The price in column 4 is the weighted average price. The price actually received ranged from $85.58 to $88.07. The reporting person shall provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. /s/ Laura Randall Woodhead, Attorney-in-Fact 2016-05-25