X0306 4 2016-02-29 0 0001048477 BIOMARIN PHARMACEUTICAL INC BMRN 0001221590 BIENAIME JEAN JACQUES C/O BIOMARIN PHARMACEUTICAL INC. 770 LINDARO ST. SAN RAFAEL CA 94901 1 1 0 0 Chief Executive Officer Common Stock 2016-02-29 2016-02-29 4 F 0 192982 81.87 D 350500 D Common Stock 2016-03-01 2016-03-01 4 S 0 5021 84.3259 D 345479 D Common Stock 2016-03-01 2016-03-01 4 S 0 2151 84.2178 D 343328 D Common Stock 2016-03-01 2016-03-01 4 S 0 2828 84.235 D 340500 D Common Stock 25758 I Shares held by Bienaime Family Trust Trade made pursuant to a 10b5-1 plan executed December 4, 2015. The price in column 4 is an average weighted price. The price actually received ranged from $81.35 to $87.11. The issuing person shall provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. The price in column 4 is an average weighted price. The price actually received ranged from $81.40 to $86.61. The issuing person shall provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.s. The price in column 4 is an average weighted price. The price actually received ranged from $81.50 to $86.98. The issuing person shall provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. /s/ Laura Randall Woodhead, Attorney-in-Fact 2016-03-02