X0306 4 2015-04-30 0 0001048477 BIOMARIN PHARMACEUTICAL INC BMRN 0001238403 SPIEGELMAN DANIEL K C/O BIOMARIN PHARMACEUTICAL INC., 770 LINDARO ST. SAN RAFAEL CA 94901 0 1 0 0 EVP, Chief Financial Officer Common Stock 2015-04-30 2015-04-30 4 A 0 88 51.2635 A 79366 D Common Stock 2015-05-15 2015-05-15 4 F 0 1722 122.78 D 77644 D Common Stock 2015-05-18 2015-05-18 4 S 0 2059 124.7717 A 75585 D The reporting person is reporting the purchase of shares of the issuer's Employee Stock Purchase Plan ("ESPP"), for the purchase period of November 1, 2014 to April 30, 2015. Trade made pursuant to a 10b5-1 plan executed on March 11, 2015. The price in column 4 is a weighted average price. The price actually received ranged from $122.00 to $125.99. The reporting person shall provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the amount of shares sold at each price within the range. /s/ Laura Randall Woodhead, Attorney-in-Fact 2015-05-19