X0306 4 2014-12-24 0 0001048477 BIOMARIN PHARMACEUTICAL INC BMRN 0001221590 BIENAIME JEAN JACQUES C/O BIOMARIN PHARMACEUTICAL INC. 770 LINDARO ST. SAN RAFAEL CA 94901 1 1 0 0 Chief Executive Officer Common Stock 2014-12-24 2014-12-24 4 M 0 3000 12.99 A 46195 I Shares held by Bienaime Family Trust Common Stock 2014-12-24 2014-12-24 4 S 0 3000 88.7310 D 43195 I Shares held by Bienaime Family Trust Common Stock 2014-12-24 2014-12-24 4 S 0 2000 88.7310 D 227157 D Stock Option (right to buy Common Stock) 12.99 2014-12-24 2014-12-24 4 M 0 3000 0 D 2006-11-11 2016-05-10 Common Stock 3000 64500 I Shares Held by Bienaime Family Trust Stock Option (right to buy Common Stock) 12.99 2006-11-11 2016-05-10 Common Stock 10000 10000 I Held in irrevocable trust for Guillaume Bienaime Stock Option (right to buy Common Stock) 12.99 2006-11-11 2016-05-10 Common Stock 10000 10000 I Held in irrevocable trust for Pierre Bienaime Stock Option (right to buy Common Stock) 12.99 2006-11-11 2016-05-10 Common Stock 10000 10000 I Held in irrevocable trust for Paul Bienaime Stock Option (right to buy Common Stock) 12.99 2006-11-11 2016-05-10 Common Stock 10000 10000 I Held in irrevocable trust for Marc Bienaime Stock Option (right to buy Common Stock) 12.99 2006-11-11 2016-05-10 Common Stock 20000 20000 I Held in irrevocable trust for Aurelie Mitsuki Bienaime & Anais Kimiko Bienaime Trade made pursuant to a 10b5-1 plan executed November 6, 2014 The reporting person an his spouse act as trustees for the Bienaime Family Trust The price in column 4 is an average weighted price. The price actually received ranged from $87.00 to $89.41. The issuing person shall provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the amount of shares sold at each price within the range. Original option grant vests 6/48ths on November 11, 2006, and 1/48th on the 11th of every month thereafter. Reflects the number of stock options outstanding after the transaction from this specific stock option grant. The reporting person's spouse is the trustee of each child's trust. /s/ Laura Randall Woodhead, Attorney-in-Fact 2014-12-29