X0303 4 2010-10-29 0 0001048477 BIOMARIN PHARMACEUTICAL INC BMRN 0001197355 FUCHS HENRY J C/O BIOMARIN PHARMACEUTICAL INC. 105 DIGITAL DRIVE NOVATO CA 94949 0 1 0 0 EVP, Chief Medical Officer Common Stock 2010-10-29 2010-10-29 4 A 0 1602 13.226 A 32602 D Common Stock 2010-11-01 2010-11-01 4 M 0 833 11.05 A 33435 D Common Stock 2010-11-01 2010-11-01 4 S 0 1602 25.7549 D 31833 D Common Stock 2010-11-01 2010-11-01 4 S 0 833 25.7644 D 31000 D Stock Option (right to buy) 11.05 2010-11-01 2010-11-01 4 M 0 833 0 D 2009-09-02 2019-03-01 Common Stock 833 230334 D Transaction made pursuant to Employee Stock Purchase Plan. Transaction made pursuant to a Rule 105-1 Trading plan executed on March 3, 2010. The price in Column 4 is a weighted average price. The prices actually received range from $25.64 to $25.84. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. The price in Column 4 is a weighted average price. The prices actually received range from $25.69 to $25.84. The reporting person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price within the range. Original option grant vests 6/48ths on September 2, 2009 and 1/48th on the 2nd of each month thereafter. /s/ Laura Randall Woodhead, Attorney-in-Fact 2010-11-02