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SEGMENT INFORMATION - Schedule of Reportable Segment Information (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Revenue from External Customer [Line Items]      
Total revenues $ 3,221,253 $ 2,853,915 $ 2,419,226
Cost of sales 717,442 580,235 532,062
Research and development 921,930 747,184 746,773
NET INCOME 348,901 426,859 167,645
Reportable Segment      
Revenue from External Customer [Line Items]      
Total revenues 3,221,253 2,853,915 2,419,226
Cost of sales 717,442 580,235 532,062
S&M expenses 530,156 476,739 488,442
G&A expenses 622,861 532,286 403,964
Other segment expense, net 79,963 90,612 80,340
NET INCOME 348,901 426,859 167,645
Research and early pipeline | Reportable Segment      
Revenue from External Customer [Line Items]      
Research and development 383,705 434,023 393,078
Later-stage clinical programs | Reportable Segment      
Revenue from External Customer [Line Items]      
Research and development 308,334 27,581 62,604
Marketed products | Reportable Segment      
Revenue from External Customer [Line Items]      
Research and development $ 229,891 $ 285,580 $ 291,091