SEGMENT INFORMATION - Schedule of Reportable Segment Information (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024
Revenue from External Customer [Line Items]
Total revenues	$ 776,133	$ 745,740	$ 2,346,688	$ 2,106,602
Cost of sales	140,085	188,457	441,733	444,096
R&D expenses	409,478	184,901	729,517	573,675
NET INCOME (LOSS)	(30,744)	106,080	395,474	301,916
Reportable Segment
Revenue from External Customer [Line Items]
Total revenues	776,133	745,740	2,346,688	2,106,602
Cost of sales	140,085	188,457	441,733	444,096
S&M expenses	131,327	108,945	355,958	351,103
G&A expenses	137,088	144,535	350,852	391,315
Other segment expense (income), net	(11,101)	12,822	73,154	44,497
NET INCOME (LOSS)	(30,744)	106,080	395,474	301,916
Research and early pipeline | Reportable Segment
Revenue from External Customer [Line Items]
R&D expenses	93,720	104,915	280,158	331,372
Later-stage clinical programs | Reportable Segment
Revenue from External Customer [Line Items]
R&D expenses	251,650	10,078	279,074	17,792
Marketed products | Reportable Segment
Revenue from External Customer [Line Items]
R&D expenses	$ 64,108	$ 69,908	$ 170,285	$ 224,511