SEGMENT INFORMATION - Schedule of Total Revenues and Disaggregates Net Product Revenues by Product (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024	Jun. 30, 2025	Jun. 30, 2024
Revenue from External Customer [Line Items]
Total revenues	$ 825,410	$ 712,029	$ 1,570,555	$ 1,360,862
Net product revenues
Revenue from External Customer [Line Items]
Total revenues	812,982	702,129	1,547,626	1,339,944
VOXZOGO
Revenue from External Customer [Line Items]
Total revenues	221,391	183,923	435,145	336,812
VIMIZIM
Revenue from External Customer [Line Items]
Total revenues	215,424	178,016	403,770	370,536
NAGLAZYME
Revenue from External Customer [Line Items]
Total revenues	128,867	132,049	243,157	237,678
PALYNZIQ
Revenue from External Customer [Line Items]
Total revenues	105,938	88,291	199,207	164,000
ALDURAZYME
Revenue from External Customer [Line Items]
Total revenues	56,437	38,558	105,414	73,820
BRINEURA
Revenue from External Customer [Line Items]
Total revenues	48,692	45,309	89,054	84,356
KUVAN
Revenue from External Customer [Line Items]
Total revenues	27,034	28,551	52,170	64,461
ROCTAVIAN
Revenue from External Customer [Line Items]
Total revenues	9,199	7,432	19,709	8,281
Royalty and other revenues
Revenue from External Customer [Line Items]
Total revenues	$ 12,428	$ 9,900	$ 22,929	$ 20,918