SEGMENT INFORMATION - Summary of Reportable Segment Information (Details) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024	Jun. 30, 2025	Jun. 30, 2024
Revenue from External Customer [Line Items]
Total revenues	$ 825,410	$ 712,029	$ 1,570,555	$ 1,360,862
Cost of sales	150,090	130,459	301,648	255,639
R&D expenses	161,308	183,787	320,039	388,774
NET INCOME	240,532	107,174	426,218	195,836
Reportable Segment
Revenue from External Customer [Line Items]
Total revenues	825,410	712,029	1,570,555	1,360,862
Cost of sales	150,090	130,459	301,648	255,639
S&M expenses	122,100	122,798	224,631	242,158
G&A expenses	110,179	140,234	213,764	246,780
Other segment expense, net	41,201	27,577	84,255	31,675
Research and early pipeline | Reportable Segment
Revenue from External Customer [Line Items]
R&D expenses	95,968	106,063	186,438	226,455
Later-stage clinical programs | Reportable Segment
Revenue from External Customer [Line Items]
R&D expenses	13,133	7,714	27,424	7,714
Marketed products | Reportable Segment
Revenue from External Customer [Line Items]
R&D expenses	$ 52,207	$ 70,010	$ 106,177	$ 154,605