CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024	Jun. 30, 2025	Jun. 30, 2024
REVENUES:
Total revenues	$ 825,410	$ 712,029	$ 1,570,555	$ 1,360,862
OPERATING EXPENSES:
Cost of sales	150,090	130,459	301,648	255,639
Research and development	161,308	183,787	320,039	388,774
Selling, general and administrative	232,279	263,032	438,395	488,938
Intangible asset amortization	4,846	14,299	9,693	28,597
Gain on sale of nonfinancial assets	0	0	0	(10,000)
Total operating expenses	548,523	591,577	1,069,775	1,151,948
INCOME FROM OPERATIONS	276,887	120,452	500,780	208,914
Interest income	18,827	19,785	37,840	39,150
Interest expense	(2,679)	(3,574)	(5,542)	(7,121)
Other income (expense), net	4,833	(4,527)	2,879	(3,260)
INCOME BEFORE INCOME TAXES	297,868	132,136	535,957	237,683
Provision for income taxes	57,336	24,962	109,739	41,847
NET INCOME	$ 240,532	$ 107,174	$ 426,218	$ 195,836
EARNINGS PER SHARE, BASIC (in dollars per share)	$ 1.25	$ 0.56	$ 2.23	$ 1.03
EARNINGS PER SHARE, DILUTED (in dollars per share)	$ 1.23	$ 0.55	$ 2.19	$ 1.01
Weighted average common shares outstanding, basic (in shares)	191,907	190,114	191,440	189,490
Weighted average common shares outstanding, diluted (in shares)	197,091	200,505	196,643	200,137
COMPREHENSIVE INCOME	$ 176,816	$ 135,019	$ 320,000	$ 251,423
Net product revenues
REVENUES:
Total revenues	812,982	702,129	1,547,626	1,339,944
Royalty and other revenues
REVENUES:
Total revenues	$ 12,428	$ 9,900	$ 22,929	$ 20,918