INCOME TAXES - Schedule of Net Operating Loss and Tax Credit Carryforwards (Details) $ in Thousands	Dec. 31, 2024 USD ($)
Federal
Income Tax Contingency [Line Items]
Net operating loss carryforwards	$ 2,964
Federal R&D and orphan drug credit carryforwards	496,532
State
Income Tax Contingency [Line Items]
Net operating loss carryforwards	200,696
Federal R&D and orphan drug credit carryforwards	182,500
Dutch \| Foreign
Income Tax Contingency [Line Items]
Dutch net operating loss carryforwards	$ 27,994

Amount before allocation of valuation allowances of deferred tax asset attributable to deductible operating loss carryforwards that are not subject to expiration dates.

Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
-Topic 740
-SubTopic 10
-Name Accounting Standards Codification
-Section 50
-Paragraph 6
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482685/740-10-50-6

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