CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2023	Sep. 30, 2022	Sep. 30, 2023	Sep. 30, 2022
REVENUES:
Total revenues	$ 581,329	$ 505,344	$ 1,773,019	$ 1,558,501
OPERATING EXPENSES:
Cost of sales	124,745	116,288	379,376	356,379
Research and development	191,314	157,829	540,523	476,855
Selling, general and administrative	223,928	216,816	662,267	608,270
Intangible asset amortization and contingent consideration	15,681	16,828	46,975	50,935
Gain on sale of nonfinancial assets, net	0	0	0	(108,000)
Total operating expenses	555,668	507,761	1,629,141	1,384,439
INCOME (LOSS) FROM OPERATIONS	25,661	(2,417)	143,878	174,062
Interest income	15,740	4,999	40,295	9,324
Interest expense	(3,779)	(4,679)	(11,237)	(12,344)
Other income (expense), net	4,047	193	(3,700)	(3,908)
INCOME (LOSS) BEFORE INCOME TAXES	41,669	(1,904)	169,236	167,134
Provision for income taxes	1,291	4,748	21,966	25,324
NET INCOME (LOSS)	$ 40,378	$ (6,652)	$ 147,270	$ 141,810
EARNINGS (LOSS) PER SHARE, BASIC (in dollars per share)	$ 0.21	$ (0.04)	$ 0.78	$ 0.77
EARNINGS (LOSS) PER SHARE, DILUTED (in dollars per share)	$ 0.21	$ (0.04)	$ 0.77	$ 0.75
Weighted average common shares outstanding, basic (in shares)	188,219	185,597	187,617	185,009
Weighted average common shares outstanding, diluted (in shares)	191,173	185,597	195,042	192,252
COMPREHENSIVE INCOME	$ 65,252	$ 5,625	$ 157,394	$ 158,127
Net product revenues
REVENUES:
Total revenues	568,266	493,348	1,739,390	1,516,533
Royalty and other revenues
REVENUES:
Total revenues	$ 13,063	$ 11,996	$ 33,629	$ 41,968