PROPERTY, PLANT AND EQUIPMENT (Tables)

12 Months Ended

Dec. 31, 2021

Property, Plant and Equipment [Abstract]

Schedule of Property Plant and Equipment Net

Property, Plant and Equipment, Net, consisted of the following:

	December 31,
	2021		2020
Building and improvements	$	774,923	$	761,560
Manufacturing and laboratory equipment	444,182		414,439
Computer hardware and software	201,382		189,740
Land	90,418		90,418
Leasehold improvements	55,279		55,134
Furniture and equipment	42,976		40,223
Land improvements	10,132		7,412
Construction-in-progress	136,743		109,140
	1,756,035		1,668,066
Accumulated depreciation	(720,574)		(635,595)
Total property, plant and equipment, net	$	1,035,461	$	1,032,471