Revenue, Credit Concentrations and Geographic Information - Disaggregates of Total Revenues from External Customers and Collaborative Partners by Geographic Region (Detail) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2020	Sep. 30, 2019	Sep. 30, 2020	Sep. 30, 2019
Revenue from External Customer [Line Items]
Total revenues	$ 476,784	$ 461,097	$ 1,408,338	$ 1,249,605
United States
Revenue from External Customer [Line Items]
Total revenues	252,948	201,874	729,672	562,217
Europe
Revenue from External Customer [Line Items]
Total revenues	121,158	125,485	375,453	369,585
Latin America
Revenue from External Customer [Line Items]
Total revenues	44,064	83,799	141,852	164,132
Rest of world
Revenue from External Customer [Line Items]
Total revenues	$ 58,614	$ 49,939	$ 161,361	$ 153,671