Property Plant and Equipment - Schedule of Property Plant and Equipment Net (Detail) - USD ($) $ in Thousands	Sep. 30, 2020	Dec. 31, 2019
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	$ 1,628,745	$ 1,559,968
Accumulated depreciation	(613,683)	(549,100)
Total property, plant and equipment, net	1,015,062	1,010,868	[1]
Building and improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	756,479	725,906
Manufacturing and laboratory equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	402,357	366,951
Computer hardware and software
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	187,722	167,554
Land
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	7,349	7,349
Leasehold improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	90,418	90,418
Furniture and equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	52,479	51,324
Land improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	39,360	38,569
Construction-in-progress
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	$ 92,581	$ 111,897

[1] December 31, 2019 balances were derived from the audited Consolidated Financial Statements included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2019, filed with the SEC on February 27, 2020.