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PROPERTY, PLANT AND EQUIPMENT (Tables)
9 Months Ended
Sep. 30, 2020
Property, Plant and Equipment [Abstract]  
Schedule of Property Plant and Equipment Net
Property, plant and equipment, net consisted of the following: 
September 30,
2020
December 31,
2019
Building and improvements$756,479 $725,906 
Manufacturing and laboratory equipment402,357 366,951 
Computer hardware and software187,722 167,554 
Land90,418 90,418 
Leasehold improvements52,479 51,324 
Furniture and equipment39,360 38,569 
Land improvements7,349 7,349 
Construction-in-progress92,581 111,897 
1,628,745 1,559,968 
Accumulated depreciation(613,683)(549,100)
Total property, plant and equipment, net$1,015,062 $1,010,868 
Three Months Ended
September 30,
Nine Months Ended
September 30,
2020201920202019
Depreciation expense$22,187 $24,238 $65,749 $67,206 
Depreciation capitalized into inventory$10,883 $9,807 $34,053 $24,894