CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2020		Jun. 30, 2019
CASH FLOWS FROM OPERATING ACTIVITIES:
Net income (loss)	$ 52,198		$ (93,908)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	51,180		48,771
Non-cash interest expense	9,534		8,870
Amortization of premium (accretion of discount) on investments	38		(1,510)
Stock-based compensation	91,956		82,590
Gain on sale of nonfinancial assets	(59,495)		(15,000)
Deferred income taxes	(5,864)		(10,083)
Unrealized foreign exchange loss	2,201		799
Non-cash changes in the fair value of contingent consideration	(584)		4,891
Other	(650)		(3,603)
Changes in operating assets and liabilities:
Accounts receivable, net	(8,028)		(31,030)
Inventory	(46,298)		(33,119)
Other current assets	20,441		(4,989)
Other assets	(5,599)		(4,593)
Accounts payable and accrued liabilities	(94,425)		(37,571)
Other long-term liabilities	5,938		10,279
Net cash provided by (used in) operating activities	12,543		(79,206)
CASH FLOWS FROM INVESTING ACTIVITIES:
Purchases of property, plant and equipment	(66,716)		(61,387)
Maturities and sales of investments	170,111		423,477
Purchases of available-for-sale securities	(321,684)		(386,320)
Proceeds from sale of nonfinancial assets	67,159		0
Purchase of intangible assets	(10,786)		(5,770)
Investment in convertible note	(8,709)		0
Other	(722)		(808)
Net cash used in investing activities	(171,347)		(30,808)
CASH FLOWS FROM FINANCING ACTIVITIES:
Proceeds from exercises of awards under equity incentive plans	46,927		19,013
Taxes paid related to net share settlement of equity awards	(36,645)		(36,900)
Payment of contingent acquisition consideration	0		(57,507)
Repurchase of common stock	(50,000)		0
Proceeds from convertible senior subordinated note offering, net	585,782		0
Principal repayments of financing leases	(2,047)		(1,347)
Net cash provided by (used in) financing activities	544,017		(76,741)
Effect of exchange rate changes on cash	(3,759)		350
NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS	381,454		(186,405)
Cash and cash equivalents:
Beginning of period	437,446	[1]	493,982
End of period	818,900		307,577
SUPPLEMENTAL CASH FLOW DISCLOSURES:
Cash paid for income taxes	2,960		3,933
Cash paid for interest	4,154		4,295
SUPPLEMENTAL CASH FLOW DISCLOSURES FOR NON-CASH INVESTING AND FINANCING ACTIVITIES:
Decrease in accounts payable and accrued liabilities related to fixed assets	(23,259)		(3,467)
Increase (decrease) in accounts payable and accrued liabilities related to intangible assets	$ (2,523)		$ 1,691

[1] December 31, 2019 balances were derived from the audited Consolidated Financial Statements included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2019, filed with the SEC on February 27, 2020.