Derivative Instruments and Hedging Strategies - Summary of Impact of Gains and Losses from Derivatives Designated as Hedging Instruments (Detail) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2020	Jun. 30, 2019	Jun. 30, 2020	Jun. 30, 2019
Derivative Instruments, Gain (Loss) [Line Items]
Net product revenues	$ 429,485	$ 387,763	$ 931,554	$ 788,508
Operating expenses as reported	470,430	429,117	867,538	883,813
Not Designated as Hedging Instrument
Derivative Instruments, Gain (Loss) [Line Items]
Gains (Losses) Recognized in Earnings	1,729	(918)	5,538	(3,896)
Operating Expense | Derivatives Designated As Hedging Instruments | Accumulated Gain (Loss), Net, Cash Flow Hedge, Parent
Derivative Instruments, Gain (Loss) [Line Items]
Cash Flow Hedging Gains (Losses) Reclassified into Earnings	(1,786)	(768)	(3,459)	(497)
Net product revenues
Derivative Instruments, Gain (Loss) [Line Items]
Net product revenues	419,032	379,075	908,075	773,558
Net product revenues | Derivatives Designated As Hedging Instruments | Accumulated Gain (Loss), Net, Cash Flow Hedge, Parent
Derivative Instruments, Gain (Loss) [Line Items]
Cash Flow Hedging Gains (Losses) Reclassified into Earnings	$ 8,279	$ 4,280	$ 14,608	$ 4,975