Revenue, Credit Concentrations and Geographic Information - Disaggregates of Total Revenues from External Customers and Collaborative Partners by Geographic Region (Detail) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2019	Sep. 30, 2018	Sep. 30, 2019	Sep. 30, 2018
Revenue from External Customer [Line Items]
Total revenues	$ 461,097	$ 391,706	$ 1,249,605	$ 1,137,998
United States
Revenue from External Customer [Line Items]
Total revenues	201,874	174,722	562,217	528,082
Europe
Revenue from External Customer [Line Items]
Total revenues	125,485	111,069	369,585	323,940
Latin America
Revenue from External Customer [Line Items]
Total revenues	83,799	75,400	164,132	151,955
Rest of world
Revenue from External Customer [Line Items]
Total revenues	$ 49,939	$ 30,515	$ 153,671	$ 134,021