Property Plant and Equipment - Schedule of Property Plant and Equipment Net (Detail) - USD ($) $ in Thousands	Sep. 30, 2019	Dec. 31, 2018
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	$ 1,504,909	$ 1,421,317
Accumulated depreciation	(535,609)	(472,635)
Total property, plant and equipment, net	969,300	948,682	[1]
Building and improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	709,990	694,447
Manufacturing and laboratory equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	365,348	345,947
Computer hardware and software
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	165,235	157,787
Leasehold improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	52,379	41,188
Furniture and equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	37,603	33,234
Land improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	7,239	6,551
Land
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	83,094	77,993
Construction-in-progress
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	$ 84,021	$ 64,170

[1] December 31, 2018 balances were derived from the audited Consolidated Financial Statements included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2018, filed with the SEC on February 28, 2019.