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PROPERTY, PLANT AND EQUIPMENT (Tables)
9 Months Ended
Sep. 30, 2019
Property, Plant and Equipment [Abstract]  
Schedule of Property Plant and Equipment Net
Property, plant and equipment, net consisted of the following: 
 
September 30,
2019
 
December 31,
2018
Building and improvements
$
709,990

 
$
694,447

Manufacturing and laboratory equipment
365,348

 
345,947

Computer hardware and software
165,235

 
157,787

Leasehold improvements
52,379

 
41,188

Furniture and equipment
37,603

 
33,234

Land improvements
7,239

 
6,551

Land
83,094

 
77,993

Construction-in-progress
84,021

 
64,170

 
1,504,909

 
1,421,317

Accumulated depreciation
(535,609
)
 
(472,635
)
Total property, plant and equipment, net
$
969,300

 
$
948,682