Property Plant and Equipment - Schedule of Property Plant and Equipment Net (Detail) - USD ($) $ in Thousands	Jun. 30, 2019	Dec. 31, 2018
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	$ 1,477,972	$ 1,421,317
Accumulated depreciation	(515,002)	(472,635)
Total property, plant and equipment, net	962,970	948,682	[1]
Building and improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	701,060	694,447
Manufacturing and laboratory equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	357,049	345,947
Computer hardware and software
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	162,696	157,787
Leasehold improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	50,502	41,188
Furniture and equipment
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	36,229	33,234
Land improvements
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	7,253	6,551
Land
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	77,994	77,993
Construction-in-progress
Property, Plant and Equipment [Line Items]
Property, plant and equipment, gross	$ 85,189	$ 64,170

[1] December 31, 2018 balances were derived from the audited Consolidated Financial Statements included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2018, filed with the SEC on February 28, 2019.