<?xml version="1.0" encoding="us-ascii"?>
<!--XBRL document created by Donnelley Financial Solutions IM Processor 9.1.2.0 using Fujitsu Interstage XWand-->
<xbrl xmlns:gsvit="http://www.gsamfunds.com/20190624" xmlns:dei="http://xbrl.sec.gov/dei/2018-01-31" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:rr="http://xbrl.sec.gov/rr/2018-01-31" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:iso4217="http://www.xbrl.org/2003/iso4217" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xbrldi="http://xbrl.org/2006/xbrldi" xmlns="http://www.xbrl.org/2003/instance">
  <link:schemaRef xlink:type="simple" xlink:href="gsvit-20190624.xsd" />
  <context id="Duration_30Apr2019_30Apr2019">
    <entity>
      <identifier scheme="http://www.sec.gov/CIK">0001046292</identifier>
    </entity>
    <period>
      <startDate>2019-04-30</startDate>
      <endDate>2019-04-30</endDate>
    </period>
  </context>
  <context id="Duration_30Apr2019_30Apr2019S000044541_Member">
    <entity>
      <identifier scheme="http://www.sec.gov/CIK">0001046292</identifier>
      <segment>
        <xbrldi:explicitMember dimension="dei:LegalEntityAxis">gsvit:S000044541Member</xbrldi:explicitMember>
      </segment>
    </entity>
    <period>
      <startDate>2019-04-30</startDate>
      <endDate>2019-04-30</endDate>
    </period>
  </context>
  <rr:ProspectusDate contextRef="Duration_30Apr2019_30Apr2019">2019-04-30</rr:ProspectusDate>
  <dei:DocumentType contextRef="Duration_30Apr2019_30Apr2019">497</dei:DocumentType>
  <dei:DocumentPeriodEndDate contextRef="Duration_30Apr2019_30Apr2019">2018-12-31</dei:DocumentPeriodEndDate>
  <dei:EntityRegistrantName contextRef="Duration_30Apr2019_30Apr2019">GOLDMAN SACHS VARIABLE INSURANCE TRUST</dei:EntityRegistrantName>
  <dei:EntityCentralIndexKey contextRef="Duration_30Apr2019_30Apr2019">0001046292</dei:EntityCentralIndexKey>
  <dei:AmendmentFlag contextRef="Duration_30Apr2019_30Apr2019">false</dei:AmendmentFlag>
  <dei:DocumentCreationDate contextRef="Duration_30Apr2019_30Apr2019">2019-06-24</dei:DocumentCreationDate>
  <dei:DocumentEffectiveDate contextRef="Duration_30Apr2019_30Apr2019">2019-06-24</dei:DocumentEffectiveDate>
  <rr:SupplementToProspectusTextBlock contextRef="Duration_30Apr2019_30Apr2019">&lt;p style="margin-top:0pt; margin-bottom:0pt;  " align="center"&gt;&lt;b&gt;GOLDMAN SACHS VARIABLE INSURANCE TRUST &lt;/b&gt;&lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt;  " align="center"&gt;Institutional, Service and Advisor Shares &lt;/p&gt; &lt;p style="margin-top:0pt; margin-bottom:0pt;  " align="center"&gt;of the &lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt;  " align="center"&gt;&lt;b&gt;Goldman Sachs Multi-Strategy Alternatives Portfolio &lt;/b&gt;&lt;/p&gt; &lt;p style="margin-top:0pt; margin-bottom:0pt;  " align="center"&gt;&lt;b&gt;(the &amp;#8220;Portfolio&amp;#8221;) &lt;/b&gt;&lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt;  " align="center"&gt;Supplement dated June&amp;nbsp;24, 2019 to the &lt;/p&gt; &lt;p style="margin-top:0pt; margin-bottom:0pt;  " align="center"&gt;Prospectuses, Summary Prospectuses and Statement of Additional Information (&amp;#8220;SAI&amp;#8221;), &lt;/p&gt; &lt;p style="margin-top:0pt; margin-bottom:0pt;  " align="center"&gt;each dated April&amp;nbsp;30, 2019 &lt;/p&gt; &lt;p style="margin-top:18pt; margin-bottom:0pt;  "&gt;Effective on or around June 28, 2019, the Portfolio may invest in the Goldman Sachs Tactical Tilt Overlay Fund (the &amp;#8220;Underlying Tactical Fund&amp;#8221;), a mutual fund for which Goldman Asset Management L.P. acts as investment adviser. In addition, the Portfolio will no longer invest in the Goldman Sachs Tactical Exposure Fund, an underlying fund of the Portfolio. &lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt;  "&gt;&lt;b&gt;Accordingly, effective on or around June 28, 2019, the Portfolio&amp;#8217;s disclosures are modified as follows: &lt;/b&gt;&lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt;  "&gt;&lt;b&gt;The following risks are added to the &amp;#8220;&lt;/b&gt;&lt;b&gt;Goldman Sachs Multi-Strategy Alternatives Portfolio&amp;#8212;Summary&amp;#8212;Principal Risks of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; section of the Prospectuses and to the &amp;#8220;&lt;/b&gt;&lt;b&gt;Principal Risks of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; section of the Summary Prospectuses: &lt;/b&gt;&lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt; margin-left:2%;  "&gt;&lt;b&gt;Asset Allocation Risk.&lt;/b&gt;&amp;nbsp;&amp;nbsp;The Goldman Sachs Tactical Tilt Overlay Fund&amp;#8217;s (&amp;#8220;Underlying Tactical Fund&amp;#8221;) allocations to various asset classes may cause the Underlying Tactical Fund to underperform other funds with a similar investment objective. &lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt; margin-left:2%;  "&gt;&lt;b&gt;Concentration Risk.&lt;/b&gt;&amp;nbsp;&amp;nbsp;If the Underlying Tactical Fund invests a substantial portion of its total assets in issuers within the same country, state, region, currency or economic sector, an adverse economic, business or political development may affect the value of the Underlying Tactical Fund&amp;#8217;s investments more than if its investments were not so concentrated. &lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt; margin-left:2%;  "&gt;&lt;b&gt;Investing in the Underlying Funds.&lt;/b&gt;&amp;nbsp;&amp;nbsp;The Underlying Tactical Fund&amp;#8217;s investment performance may be directly related to the investment performance of the underlying funds it holds. The ability of the Underlying Tactical Fund to meet its investment objective is directly related to the ability of its underlying funds to meet their objectives as well as the allocation among those underlying funds by the Investment Adviser. &lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt;  "&gt;&lt;b&gt;In the &amp;#8220;&lt;/b&gt;&lt;b&gt;Goldman Sachs Multi-Strategy Alternatives Portfolio&amp;#8212;Summary&amp;#8212;Principal Risks of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; and &amp;#8220;&lt;/b&gt;&lt;b&gt;Risks of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; sections of the Prospectuses, and in the &amp;#8220;&lt;/b&gt;&lt;b&gt;Principal Risks of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; section of the Summary Prospectuses, the sections titled &amp;#8220;&lt;/b&gt;&lt;b&gt;GPS Transactions Risk&lt;/b&gt;&lt;b&gt;&amp;#8221; and &amp;#8220;&lt;/b&gt;&lt;b&gt;Temporary Investments Risk&lt;/b&gt;&lt;b&gt;&amp;#8221; are deleted in their entirety. &lt;/b&gt;&lt;/p&gt;  &lt;p style="page-break-before:always"&gt; &lt;/p&gt; &lt;p style="margin-top:0pt; margin-bottom:0pt;  "&gt;&lt;b&gt;In the &amp;#8220;&lt;/b&gt;&lt;b&gt;Goldman Sachs Multi-Strategy Alternatives Portfolio&amp;#8212;Summary&amp;#8212;Principal Risks of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; and &amp;#8220;&lt;/b&gt;&lt;b&gt;Risks of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; sections of the Prospectuses, and in the &amp;#8220;&lt;/b&gt;&lt;b&gt;Principal Risks of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; section of the Summary Prospectuses, references to the &amp;#8220;Underlying Tactical Exposure Fund&amp;#8221; are replaced with &amp;#8220;Underlying Tactical Fund&amp;#8221; in the &amp;#8220;&lt;/b&gt;&lt;b&gt;Investments in Affiliated Underlying Funds&lt;/b&gt;&lt;b&gt;,&amp;#8221; &amp;#8220;&lt;/b&gt;&lt;b&gt;Investments in ETFs&lt;/b&gt;&lt;b&gt;&amp;#8221; and &amp;#8220;&lt;/b&gt;&lt;b&gt;Investments of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; sections. &lt;/b&gt;&lt;/p&gt;</rr:SupplementToProspectusTextBlock>
  <rr:SupplementToProspectusTextBlock contextRef="Duration_30Apr2019_30Apr2019S000044541_Member">&lt;p style="margin-top:0pt; margin-bottom:0pt;  " align="center"&gt;&lt;b&gt;GOLDMAN SACHS VARIABLE INSURANCE TRUST &lt;/b&gt;&lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt;  " align="center"&gt;Institutional, Service and Advisor Shares &lt;/p&gt; &lt;p style="margin-top:0pt; margin-bottom:0pt;  " align="center"&gt;of the &lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt;  " align="center"&gt;&lt;b&gt;Goldman Sachs Multi-Strategy Alternatives Portfolio &lt;/b&gt;&lt;/p&gt; &lt;p style="margin-top:0pt; margin-bottom:0pt;  " align="center"&gt;&lt;b&gt;(the &amp;#8220;Portfolio&amp;#8221;) &lt;/b&gt;&lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt;  " align="center"&gt;Supplement dated June&amp;nbsp;24, 2019 to the &lt;/p&gt; &lt;p style="margin-top:0pt; margin-bottom:0pt;  " align="center"&gt;Prospectuses, Summary Prospectuses and Statement of Additional Information (&amp;#8220;SAI&amp;#8221;), &lt;/p&gt; &lt;p style="margin-top:0pt; margin-bottom:0pt;  " align="center"&gt;each dated April&amp;nbsp;30, 2019 &lt;/p&gt; &lt;p style="margin-top:18pt; margin-bottom:0pt;  "&gt;Effective on or around June 28, 2019, the Portfolio may invest in the Goldman Sachs Tactical Tilt Overlay Fund (the &amp;#8220;Underlying Tactical Fund&amp;#8221;), a mutual fund for which Goldman Asset Management L.P. acts as investment adviser. In addition, the Portfolio will no longer invest in the Goldman Sachs Tactical Exposure Fund, an underlying fund of the Portfolio. &lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt;  "&gt;&lt;b&gt;Accordingly, effective on or around June 28, 2019, the Portfolio&amp;#8217;s disclosures are modified as follows: &lt;/b&gt;&lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt;  "&gt;&lt;b&gt;The following risks are added to the &amp;#8220;&lt;/b&gt;&lt;b&gt;Goldman Sachs Multi-Strategy Alternatives Portfolio&amp;#8212;Summary&amp;#8212;Principal Risks of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; section of the Prospectuses and to the &amp;#8220;&lt;/b&gt;&lt;b&gt;Principal Risks of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; section of the Summary Prospectuses: &lt;/b&gt;&lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt; margin-left:2%;  "&gt;&lt;b&gt;Asset Allocation Risk.&lt;/b&gt;&amp;nbsp;&amp;nbsp;The Goldman Sachs Tactical Tilt Overlay Fund&amp;#8217;s (&amp;#8220;Underlying Tactical Fund&amp;#8221;) allocations to various asset classes may cause the Underlying Tactical Fund to underperform other funds with a similar investment objective. &lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt; margin-left:2%;  "&gt;&lt;b&gt;Concentration Risk.&lt;/b&gt;&amp;nbsp;&amp;nbsp;If the Underlying Tactical Fund invests a substantial portion of its total assets in issuers within the same country, state, region, currency or economic sector, an adverse economic, business or political development may affect the value of the Underlying Tactical Fund&amp;#8217;s investments more than if its investments were not so concentrated. &lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt; margin-left:2%;  "&gt;&lt;b&gt;Investing in the Underlying Funds.&lt;/b&gt;&amp;nbsp;&amp;nbsp;The Underlying Tactical Fund&amp;#8217;s investment performance may be directly related to the investment performance of the underlying funds it holds. The ability of the Underlying Tactical Fund to meet its investment objective is directly related to the ability of its underlying funds to meet their objectives as well as the allocation among those underlying funds by the Investment Adviser. &lt;/p&gt; &lt;p style="margin-top:6pt; margin-bottom:0pt;  "&gt;&lt;b&gt;In the &amp;#8220;&lt;/b&gt;&lt;b&gt;Goldman Sachs Multi-Strategy Alternatives Portfolio&amp;#8212;Summary&amp;#8212;Principal Risks of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; and &amp;#8220;&lt;/b&gt;&lt;b&gt;Risks of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; sections of the Prospectuses, and in the &amp;#8220;&lt;/b&gt;&lt;b&gt;Principal Risks of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; section of the Summary Prospectuses, the sections titled &amp;#8220;&lt;/b&gt;&lt;b&gt;GPS Transactions Risk&lt;/b&gt;&lt;b&gt;&amp;#8221; and &amp;#8220;&lt;/b&gt;&lt;b&gt;Temporary Investments Risk&lt;/b&gt;&lt;b&gt;&amp;#8221; are deleted in their entirety. &lt;/b&gt;&lt;/p&gt;  &lt;p style="page-break-before:always"&gt; &lt;/p&gt; &lt;p style="margin-top:0pt; margin-bottom:0pt;  "&gt;&lt;b&gt;In the &amp;#8220;&lt;/b&gt;&lt;b&gt;Goldman Sachs Multi-Strategy Alternatives Portfolio&amp;#8212;Summary&amp;#8212;Principal Risks of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; and &amp;#8220;&lt;/b&gt;&lt;b&gt;Risks of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; sections of the Prospectuses, and in the &amp;#8220;&lt;/b&gt;&lt;b&gt;Principal Risks of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; section of the Summary Prospectuses, references to the &amp;#8220;Underlying Tactical Exposure Fund&amp;#8221; are replaced with &amp;#8220;Underlying Tactical Fund&amp;#8221; in the &amp;#8220;&lt;/b&gt;&lt;b&gt;Investments in Affiliated Underlying Funds&lt;/b&gt;&lt;b&gt;,&amp;#8221; &amp;#8220;&lt;/b&gt;&lt;b&gt;Investments in ETFs&lt;/b&gt;&lt;b&gt;&amp;#8221; and &amp;#8220;&lt;/b&gt;&lt;b&gt;Investments of the Underlying Funds&lt;/b&gt;&lt;b&gt;&amp;#8221; sections. &lt;/b&gt;&lt;/p&gt;</rr:SupplementToProspectusTextBlock>
  <dei:EntityInvCompanyType contextRef="Duration_30Apr2019_30Apr2019">N-1A</dei:EntityInvCompanyType>
</xbrl>

