Exhibit 23.1

Consent of Independent Registered Public Accounting Firm

We consent to the reference to our firm under the caption “Experts” and to the use of our report dated August 26, 2010 (except as to Note 11 and paragraphs 2, 3, 4, 7 and 8 of Note 20 as to which the date is April 15, 2011, and except as to paragraph 9 of Note 20 as to which the date is            , 2011), in the Registration Statement (Form S-1) and related Prospectus of Vanguard Health Systems, Inc. for the registration of shares of its common stock.

Ernst & Young LLP

Nashville, Tennessee
          , 2011

The foregoing consent is in the form that will be signed upon completion of the 2011 stock split and increase in authorized shares described in Note 20 to the consolidated financial statements.

/s/ Ernst & Young LLP

Nashville, Tennessee
April 15, 2011