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Stock-Based Compensation - Summary of Stock Option Activity (Detail) - $ / shares
3 Months Ended 12 Months Ended
Mar. 31, 2022
Dec. 31, 2021
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]    
Number of Shares Outstanding, Beginning Balance 2,413,194  
Number of Shares, Granted 1,155,570  
Number of Shares, Cancelled/forfeited/expired (365,250)  
Number of Shares Outstanding, Ending Balance 3,203,514 2,413,194
Number of Shares, Vested and unvested expected to vest, Ending Balance 3,162,485  
Weighted Average Exercise Price Per Share, Outstanding, Beginning Balance $ 7.04  
Weighted Average Exercise Price Per Share, Granted 2.35  
Weighted Average Exercise Price Per Share, Cancelled/forfeited/expired 6.44  
Weighted Average Exercise Price Per Share, Outstanding, Ending Balance 5.50 $ 7.04
Weighted Average Exercise Price Per Share, Vested and unvested expected to vest, Ending Balance $ 5.52  
Weighted Average Remaining Contractual Term in Years, Outstanding 7 years 9 months 18 days 9 years 21 days
Weighted Average Remaining Contractual Term in Years, Vested and unvested expected to vest 7 years 9 months 10 days