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Stock-Based Compensation - Summary of Stock Option Activity (Detail) - $ / shares
9 Months Ended 12 Months Ended
Sep. 30, 2020
Dec. 31, 2019
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]    
Number of Shares Outstanding, Beginning Balance 273,406  
Number of Shares, Granted 13,870  
Number of Shares, Cancelled/forfeited/expired (32,920)  
Number of Shares Outstanding, Ending Balance 254,356 273,406
Number of Shares, Vested and unvested expected to vest, Ending Balance 250,368  
Weighted Average Exercise Price Per Share, Outstanding, Beginning Balance $ 36.14  
Weighted Average Exercise Price Per Share, Granted 5.23  
Weighted Average Exercise Price Per Share, Cancelled/forfeited/expired 16.09  
Weighted Average Exercise Price Per Share, Outstanding, Ending Balance 37.04 $ 36.14
Weighted Average Exercise Price Per Share, Vested and unvested expected to vest, Ending Balance $ 37.48  
Weighted Average Remaining Contractual Term in Years, Outstanding 8 years 6 months 9 years 3 months
Weighted Average Remaining Contractual Term in Years, Vested and unvested expected to vest 8 years 6 months