Income Taxes - Reconciles of Income Taxes Computed at Federal Statutory Rate and Provision for Income Taxes (Detail) - USD ($)	12 Months Ended
Dec. 31, 2017	Dec. 31, 2016
Income Tax Disclosure [Abstract]
Income tax at statutory rate	$ (7,346,079)	$ (6,255,072)
Change in federal tax rate	2,621,803
State liability	(411,853)	(260,835)
Permanent items	214,313	67,151
Stock compensation	72,696	157,250
Nondeductible interest	15,568	21,548
Expiration of net operating losses	922,307
Research and development credit	(200,379)	(170,950)
State rate change	(18,026)	44,421
Estimated section 382 limitation	1,491,942	9,256,295
Return to provision	365,263
Other	488,264	96,406
Valuation allowance	1,791,805	(2,954,161)
Provision for income tax	$ 7,624	$ 2,053

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Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

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