X0202 3 2006-04-30 0 0000736994 ALLIANCE PHARMACEUTICAL CORP ALLP 0001044321 MARXE AUSTIN W & GREENHOUSE DAVID M C/O SPECIAL SITUATIONS FUNDS 527 MADISON AVENUE, SUITE 2600 NEW YORK NY 10022 0 0 1 0 Corporated Bond 0.17 2006-04-30 2007-04-01 Common Stock 5867647 I By Limited Partnerships In April 2006 the conversion price of the bond was lowered to $0.17, thereby increasing the number of common shares that can be purchased. This is a joint filing by Austin W. Marxe (Marxe) and David M. Greenhouse (Greenhouse). They share voting and investment control over all securities owned by Special Situations Private Equity Fund, L.P. (PE). 997,500 of Corporate Bonds convertible into 5,867,647 shares of Common Stock are owned by PE. The interest of Marxe and Greenhouse in the shares of Common Stock owned by PE is limited to the extent of his pecuniary interest. Austin W. Marxe 2007-03-09 David M. Greenhouse 2007-03-09