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STOCKHOLDERS' EQUITY (Common Stock Warrants) (Details) - $ / shares
3 Months Ended
Mar. 31, 2017
Dec. 31, 2016
Class of Stock [Line Items]    
Class of stock warrants expired (shares) 3,362,276  
Common stock warrants issued (in shares) 2,933,106  
Underlying Shares   3,334,011
Private Placement    
Class of Stock [Line Items]    
Common stock warrants issued (in shares) 1,051,650  
Offering    
Class of Stock [Line Items]    
Common stock warrants issued (in shares) 1,881,456  
Various Institutional Holders; January 2018    
Class of Stock [Line Items]    
Underlying Shares   441,655
Exercise Price (in dollars per share)   $ 9
Affiliates of Third Security, LLC; January 2018    
Class of Stock [Line Items]    
Underlying Shares   250,000
Exercise Price (in dollars per share)   $ 9
Various Institutional Holders; April 2020    
Class of Stock [Line Items]    
Underlying Shares   374,618
Exercise Price (in dollars per share)   $ 4.00
Various Institutional Holders; February 2020    
Class of Stock [Line Items]    
Underlying Shares   714,780
Exercise Price (in dollars per share)   $ 2.24
Various Institutional Holders; December 2020    
Class of Stock [Line Items]    
Underlying Shares   122,433
Exercise Price (in dollars per share)   $ 1.66
Various Institutional Holders; January 2021    
Class of Stock [Line Items]    
Underlying Shares   1,161,972
Exercise Price (in dollars per share)   $ 1.21
Affiliates of Third Security, LLC; January 2021    
Class of Stock [Line Items]    
Underlying Shares   161,026
Exercise Price (in dollars per share)   $ 1.21
Various Institutional Holders; January 2021    
Class of Stock [Line Items]    
Underlying Shares   107,527
Exercise Price (in dollars per share)   $ 1.21