UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549


                                    FORM 8-A


                FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES
                     PURSUANT TO SECTION 12(b) OR (g) OF THE
                         SECURITIES EXCHANGE ACT OF 1934


                               TRANSGENOMIC, INC.
             ------------------------------------------------------
             (Exact name of registrant as specified in its charter)

                     DELAWARE                        91-1789357
             -----------------------             -------------------
             (State of incorporation             (IRS Employer
             or organization)                    Identification No.)

                             5600 SOUTH 42ND STREET
                                 OMAHA, NE 68107
                                 (402) 738-5480
                    ----------------------------------------
                    (Address of principal executive offices)

Securities to be registered pursuant to Section 12(b) of the Act:

     Title of each class                Name of each exchange on which
     to be so registered                each class is to be registered
     -------------------                ------------------------------

     None

If this Form relates to the registration of a class of securities pursuant to
Section 12(b) of the Exchange Act and is effective pursuant to General
Instruction A.(c), check the following box. / /

If this Form relates to the registration of a class of securities pursuant to
Section 12(g) of the Exchange Act and is effective pursuant to General
Instruction A.(d), check the following box. /X/

Securities Act registration statement file number to which this form relates (if
applicable):

     333-32174

Securities to be registered pursuant to Section 12(g) of the Act:

     Common Stock, $0.01 par value per share



Item 1.   DESCRIPTION OF SECURITIES TO BE REGISTERED

          See "Description of Securities" in Amendment No. 4 to our Registration
Statement on Form S-1 (Registration No. 333-32174) filed with the Securities and
Exchange Commission (the "Commission") on July 6, 2000, as amended prior to the
effective date thereof (collectively, the "Registration Statement"). The form of
Prospectus filed by us pursuant to Rule 424(b) promulgated under the Securities
Act of 1933, as amended, shall be deemed to be incorporated by reference into
the Registration Statement.

Item 2.   EXHIBITS

          1.   Second Amended and Restated Certificate of Incorporation of
               the Registrant (incorporated by reference to Exhibit 3.1 to
               Amendment No. 1 to the Registration Statement on Form S-1
               (No. 333-32174) filed by the Registrant on May 17, 2000).

          2.   Bylaws of the Registrant (incorporated by reference to Exhibit
               3.2 to Registration Statement on Form S-1 (No. 333-32174) filed
               by the Registrant on March 10, 2000).

          3.   Form of Certificate of Common Stock (incorporated by reference
               to Exhibit 4 to Registration Statement on Form S-1 (No.
               333-32174) filed by the Registrant on March 10, 2000).



                                    SIGNATURE

          Pursuant to the requirements of Section 12 of the Securities Exchange
Act of 1934, the Registrant has duly caused this registration statement to be
signed on its behalf by the undersigned, thereto duly authorized.


                                        TRANSGENOMIC, INC.



                                        By /s/ Collin J. D'Silva
                                           -------------------------------
                                           Collin J. D'Silva, Chairman and
                                           Chief Executive Officer

Dated: July 10, 2000