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Net Loss Per Share (Tables)
 12 Months Ended
Dec. 31, 2012
Earnings Per Share [Abstract]  
Outstanding equity awards not included in calculation of diluted net loss per share
Outstanding equity awards not included in the calculation of diluted net loss per share because their effect was anti-dilutive were as follows:
 
 
December 31, 2010
 
December 31, 2011
 
December 31, 2012
 
Number of
Potential
Shares
 
Range of
Exercise Prices
 
Number of
Potential
Shares
 
Range of
Exercise Prices
 
Number of
Potential
Shares
 
Range of
Exercise Prices
Stock options
6,179,547

 
$0.47 - $16.36

 
7,314,039

 
$0.47 - $16.36

 
8,952,129

 
$0.47 - $16.36

Unvested stock awards
2,099,523

 
$
—

 
2,221,205

 
$
—

 
655,402

 
$
—

Warrants
1,602,489

 
$
2.40

 
1,602,489

 
$
2.40

 
1,602,489

 
$
2.40